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Strategies to strengthen scientific excellence and innoVation capacIty for early diagnoSIs of gastrOintestinal caNcers

Project details

Website: http://vision.sav.sk/index.html, https://doi.org/10.3030/857381

Status: Ongoing

Project period: 2019–2022

Principal: EU (57381)

Coordinating institution: Slovak Academy of Sciences

Collaborators: NILU

Slovakia belongs to countries with the highest incidence of colorectal and pancreatic cancer in Europe. Therefore, the main goal of the VISION proposal is to strengthen the scientific excellence and innovative capacity of Biomedicinske centrum Slovenskej akademie vied (BMC SAV), in early detection of gastrointestinal cancer (GI).

Creation of a strategic partnership between the coordinator from widening county, BMC SAV and four internationally-recognized institutions, Fraunhofer-Gesellschaft zur Foerderung der Angewandten Forschung e.V. (FhG), Ramón y Cajal University Hospital Health Research Institute represented by Servicio Madrileno de Salud, (SERMAS), Ethniko Kai Kapodistriako Panepistimio Athinon (NKUA), and Norwegian Institute for Air Research (NILU) will enhance the credibility and recognition of BMC SAV in European research area.

Transfer of knowledge and research ideas, sharing of know-how, expertise and best practices, together with the implementation of cutting edge-technologies, will contribute to the enhancement of high-quality translational cancer research at BMC SAV, particularly GI cancer.

Collaboration and networking between VISION partners will accelerate the personal and professional development of early stage researchers and medical doctors, impact the rate of success in internationally competitive research funding and high-quality peer-reviewed publications.

Involvement of VISION partners in mentoring and co-supervision of PhD will increase the quality of education at universities, mainly medical and natural science faculties. Moreover, regional and outreach activities supported by VISION will lead to enhanced public awareness of cancer and the importance of prevention.

Updated: 19.09.2022

Strategies to strengthen scientific excellence and innoVation capacIty for early diagnoSIs of gastrOintestinal caNcers has 11 publications at NILU:

Nanomedicine and epigenetics: New alliances to increase the odds in pancreatic cancer survival

Urbanova, Maria; Cihova, Marina; Buocikova, Verona; Slopovsky, Jan; Dubovan, Peter; Pindak, Daniel; Tomas, Miroslav; García-Bermejo, Laura; Rodríguez-Garrote, Mercedes; Earl, Julie; Kohl, Yvonne; Kataki, Agapi; Dusinska, Maria; Sainz Jr., Bruno; Smolkova, Bozena; Gabelova, Alena


Rapid identification of in vitro cell toxicity using an electrochemical membrane screening platform

Kohl, Yvonne; William, Nicola; Elje, Elisabeth; Backes, Nadine; Rothbauer, Mario; Srancikova, Annamaria; Rundén-Pran, Elise; El Yamani, Naouale; Korenstein, Rafi; Madi, Lea; Barbul, Alexander; Kozics, Katarina; Sramkova, Monika; Steenson, Karen; Gabelova, Alena; Ertl, Peter; Dusinska, Maria; Nelson, Andrew


Genotoxic effects of occupational exposure to glass fibres – A human biomonitoring study.

Ceppi, Marcello; Smolkova, Bozena ; Staruchova, Marta; Kazimirova, Alena; Barancokova, Magdalena; Volkovova, Katarina; Collins, Andrew Richard; Kocan, Anton; Dzupinkova, Zuzana; Horska, Alexandra; Buocikova, Verona; Tulinska, Jana; Liskova, Aurelia; Mikusova, Miroslava Lehotska; Krivosikova, Zora; Wsolova, Ladislava; Kuba, Daniel; Rundén-Pran, Elise; El Yamani, Naouale; Longhin, Eleonora Marta; Halasova, Erika; Kyrtopoulos, Soterios; Bonassi, Stefano ; Dusinska, Maria


The miniaturized enzyme-modified comet assay for genotoxicity testing of nanomaterials

El Yamani, Naouale; Rundén-Pran, Elise; Collins, Andrew Richard; Longhin, Eleonora Marta; Elje, Elisabeth; Hoet, Peter; Vrček, Ivana Vinković; Doak, Shareen H.; Fessard, Valérie; Dusinska, Maria


The colony forming efficiency assay for toxicity testing of nanomaterials—Modifications for higher-throughput

Rundén-Pran, Elise; Mariussen, Espen; El Yamani, Naouale; Elje, Elisabeth; Longhin, Eleonora Marta; Dusinska, Maria


Lack of mutagenicity of TiO2 nanoparticles in vitro despite cellular and nuclear uptake

El Yamani, Naouale; Rubio, Laura; García-Rodríguez, Alba; Kažimírová, Alena; Rundén-Pran, Elise; Barančoková, Magdaléna; Marcos, Ricard; Dusinska, Maria


Hazard identification of nanomaterials: In silico unraveling of descriptors for cytotoxicity and genotoxicity

El Yamani, Naouale; Mariussen, Espen; Gromelski, Maciej; Wyrzykowska, Ewelina; Grabarek, Dawid; Puzyn, Tomasz; Tanasescu, Speranta; Dusinska, Maria; Rundén-Pran, Elise


Do cytotoxicity and cell death cause false positive results in the in vitro comet assay?

Azqueta, Amaya ; Stopper, Helga; Zegura, Bojana; Dusinska, Maria; Møller, Peter


Pharmacokinetics of PEGylated Gold Nanoparticles: In Vitro—In Vivo Correlation

Dubaj, Tibor; Kozics, Katarina; Srámková, Monika; Manova, Alena; Bastus, Neus G.; Moriones, Oscar H.; Kohl, Yvonne; Dusinska, Maria; Rundén-Pran, Elise; Puntes, Victor; Nelson, Andrew; Gábelová, Alena; Simon, Peter


Microfluidic In Vitro Platform for (Nano)Safety and (Nano)Drug Efficiency Screening

Kohl, Yvonne; Biehl, Margit; Spring, Sarah; Hesler, Michelle; Ogourtsov, Vladimir; Todorovic, Miomir; Owen, Joshua; Elje, Elisabeth; Kopecka, Kristina; Moriones, Oscar Hernando; Bastus, Neus G.; Simon, Peter; Dubaj, Tibor; Rundén-Pran, Elise; Puntes, Victor; William, Nicola; von Briesen, Hagen; Wagner, Sylvia; Kapur, Nikil; Mariussen, Espen; Nelson, Andrew; Gabelova, A; Dusinska, Maria; Velten, Thomas; Knoll, Thorsten


Genotoxicity of nanomaterials: Advanced in vitro models and high throughput methods for human hazard assessment—a review

Kohl, Yvonne; Rundén-Pran, Elise; Mariussen, Espen; Hesler, Michelle; El Yamani, Naouale; Longhin, Eleonora Marte; Dusinska, Maria