Found 9854 publications. Showing page 339 of 395:
2004
Surface warming in Svalbard may have led to increases in highly active ice-nucleating particles
The roles of Arctic aerosols as ice-nucleating particles remain poorly understood, even though their effects on cloud microphysics are crucial for assessing the climate sensitivity of Arctic mixed-phase clouds and predicting their response to Arctic warming. Here we present a full-year record of ice-nucleating particle concentrations over Svalbard, where surface warming has been anomalously faster than the Arctic average. While the variation of ice-nucleating particles active at around −30 °C was relatively small, those active at higher temperatures (i.e., highly active ice-nucleating particles) tended to increase exponentially with rising surface air temperatures when the surface air temperatures rose above 0 °C and snow/ice-free barren and vegetated areas appeared in Svalbard. The aerosol population relevant to their increase was largely characterized by dust and biological organic materials that likely originated from local/regional terrestrial sources. Our results suggest that highly active ice-nucleating particles could be actively released from Arctic natural sources in response to surface warming.
Springer Nature
2024
Surface-Bioengineered Extracellular Vesicles Seeking Molecular Biotargets in Lung Cancer Cells
Personalized medicine is a new approach to modern oncology. Here, to facilitate the application of extracellular vesicles (EVs) derived from lung cancer cells as potent advanced therapy medicinal products in lung cancer, the EV membrane was functionalized with a specific ligand for targeting purposes. In this role, the most effective heptapeptide in binding to lung cancer cells (PTHTRWA) was used. The functionalization process of EV surface was performed through the C- or N-terminal end of the heptapeptide. To prove the activity of the EVs functionalized with PTHTRWA, both a model of lipid membrane mimicking normal and cancerous cell membranes as well as human adenocarcinomic alveolar basal epithelial cells (A549) and human normal bronchial epithelial cells (BEAS-2B) have been exposed to these bioconstructs. Magnetic resonance imaging (MRI) showed that the as-bioengineered PTHTRWA-EVs loaded with superparamagnetic iron oxide nanoparticle (SPIO) cargos reach the growing tumor when dosed intravenously in NUDE Balb/c mice bearing A549 cancer. Molecular dynamics (MD) in silico studies elucidated a high affinity of the synthesized peptide to the α5β1 integrin. Preclinical safety assays did not evidence any cytotoxic or genotoxic effects of the PTHTRWA-bioengineered EVs.
American Chemical Society (ACS)
2024
2003
Survey of emissions of volatile organic chemicals from handheld toys for children above 3 years
NILU
2020
2002
On behalf of the Norwegian Ferroalloy Producers Research Association (FFF) NILU has assessed possible airborne emissions of HCB, PCB, and PCDD/F from Norwegian silicon and ferrosilicon production.
The report concludes with that the Norwegian silicon and ferrosilicon melting process does most certainly not lead to a 'de novo' formation of organochlorines. The report summaries all performed emission measurements. It states that, even in worst case, the annual contribution from Norwegian silicon and ferrosilicon production does not exceed one percent of the total annual load. Thus the contribution is regarded as negligible.
2011
2015
2017
2017
2014
Svevestøvmåling i bydel Fana langs FV546. 23. desember 2016 - 31. desember 2017.
På oppdrag fra Statens vegvesen Region vest har NILU utført målinger av PM10 og PM2.5 ved et boligområde ved Fanavegen (Bergen kommune). Støvende aktivitet i forbindelse med anleggsarbeid genererer svevestøv til sjenanse for berørte naboer. Målingene pågikk i perioden 23. desember 2016 – 31. desember 2017. Resultatene ble rapportert hver måned. Årsmiddel-konsentrasjonene for PM10 og PM2.5 i 2017 var langt under respektive grenseverdier. I måleperioden ble det observert 3 døgn med PM10-døgnmiddelverdier over grenseverdien på 50 μg/m3. Det er tillatt med 30 døgnverdier over dette nivået. Årsaken til høy PM10-konsentrasjon var oppvirvling av svevestøv fra kjørebanen. Så lenge tiltak for å dempe støvoppvirvling ble iverksatt tidsnok, var svevestøvkonsentrasjonen innenfor varslingsklassen for liten eller ingen helserisiko.
NILU
2018
2021