Found 10000 publications. Showing page 15 of 400:
2023
2008
<i>Background</i> - Concerns have been raised that extensive use of personal care products that contain endocrine disrupting compounds increase the risk of hormone sensitive cancers.<p> <p><i>Objective</i> - To assess the effect of skincare product use on the risk of pre- and postmenopausal breast cancer, estrogen receptor positive (ER+) and negative (ER-) breast cancer and cancer of the endometrium.<p> <p><i>Methods</i> - We used data from 106,978 participants in the population-based Norwegian Women and Cancer cohort. Participants were categorized into non-, light, moderate, frequent and heavy users of skincare products based on self-reported use of hand and facial cream and body lotion. Cancer incidence information from the Cancer Registry of Norway was linked to individual data through the unique identity number of Norwegian citizens. Multivariable Cox proportional hazard regression was used to assess the effect of skincare product use on the risk of cancer of the breast and endometrium. We used multiple imputation by chained equations to evaluate the effect of missing data on observed associations.<p> <p><i>Results</i> - We found no associations between use of skincare products and incidence of premenopausal breast cancer (frequent/heavy versus non−/light use: hazard ratio [HR] =1.10, 95% confidence interval [CI]: 0.92–1.32), postmenopausal breast cancer (heavy versus light use: HR = 0.87, 95% CI: 0.65–1.18, frequent versus light use: HR = 0.97, 95% CI: 0.88, 1.07) or endometrial cancer (frequent/heavy versus non−/light use: HR = 0.97, 95% CI: 0.79–1.20). Use of skincare products did not increase the risk of ER+ or ER- breast cancer and there was no difference in effect across ER status (0.58 ≤ <sub>pheterogeneity</sub> ≤ 0.99). The magnitude and direction of the effect estimates based on complete case analyses and multiple imputation were similar.<p> <p><i>Conclusion</i> Heavy use of skincare products, i.e. creaming the body up to two times per day during mid-life, did not increase the risk of cancer of the breast or endometrium.
2019
2009
Use of satellite data for atmospheric pollution and greenhouse gas monitoring. A contribution to ACCENT-TROPOSAT-2, task group 3. ACCENT reports, 1.2007
2007
2016
Use of three-dimensional (3D) tissue equivalents in toxicology has been increasing over the last decade as novel preclinical test systems and as alternatives to animal testing. In the area of genetic toxicology, progress has been made with establishing robust protocols for skin, airway (lung) and liver tissue equivalents. In light of these advancements, a “Use of 3D Tissues in Genotoxicity Testing” working group (WG) met at the 7th IWGT meeting in Tokyo in November 2017 to discuss progress with these models and how they may fit into a genotoxicity testing strategy. The workshop demonstrated that skin models have reached an advanced state of validation following over 10 years of development, while liver and airway model-based genotoxicity assays show promise but are at an early stage of development. Further effort in liver and airway model-based assays is needed to address the lack of coverage of the three main endpoints of genotoxicity (mutagenicity, clastogenicity and aneugenicity), and information on metabolic competence. The IWGT WG believes that the 3D skin comet and micronucleus assays are now sufficiently validated to undergo an independent peer review of the validation study, followed by development of individual OECD Test Guidelines.
2020
1999
2024
Usare gli oceani per catturare l'anidride carbonica? Una tecnologia ancora non matura
Per raggiungere gli obbiettivi climatici oggi bisogna dare priorità a metodi che sappiamo già essere efficaci e non creano danni ulteriori all'ambiente
2025
2006
2024
2019
2026
Urban Living Labs as Inter- and Transdisciplinary Arenas for Sustainability Planning Research
The transition towards sustainable societies necessitates inter- and transdisciplinary knowledge, particularly in urban planning, where diverse knowledge traditions are crucial for decision-making. Despite this, planning practices often remain entrenched in institutional and legal frameworks that hinder the integration of multiple ways of knowing and undervalue lay knowledge. Researcher-led urban innovation processes are increasingly adopting experimental approaches for the multi-stakeholder co-creation of knowledge, addressing urban challenges through interdisciplinary approaches. This article addresses the interdisciplinary collaboration between researchers in experimental urban planning processes by examining a research project that focused on participatory environmental co-monitoring and planning for urban air quality in Nordic contexts. The study builds a bridge between theories of interdisciplinarity, urban experimentation, and planning theory. By presenting urban living labs (ULLs) as arenas for co-learning that integrate scientific and lay knowledge, the article explores how planning researchers can facilitate mutual learning and navigate the micropolitics of knowledge co-production. We develop the concept of cross-disciplinary unknowns to highlight the dynamics and challenges in research teams with diverse epistemological backgrounds. We argue that an explicit and structured approach for explicating epistemological differences can facilitate the detection of unreflected knowledge retention between disciplines.
2026
2018