Scientific journal publication

Source term estimation of multi‐specie atmospheric release of radiation from gamma dose rates

Tichy, Ondrej; Šmídl, Václav; Hofman, Radek; Evangeliou, Nikolaos

Coffee and oxidative stress: a human intervention study

Shaposhnikov, Sergey; Hatzold, Thomas; Yamani, Naouale El; Stavro, Philip Mark; Lorenzo, Yolanda; Dusinska, Maria; Reus, Astrid; Pasman, Wilrike J.; Collins, Andrew Richard

CSF sodium at toxic levels precedes delirium in hip fracture patients

Hassel, Bjørnar; Mariussen, Espen; Idland, Ane-Victoria; Dahl, Gry Torsæter; Ræder, Johan; Frihagen, Frede Jon; Berg, Jens Petter; Chaudhry, Farrukh Abbas; Wyller, Torgeir Bruun; Watne, Leiv

The value of coastal lagoons: Case study of recreation at the Ria de Aveiro, Portugal in comparison to the Coorong, Australia

Clara, Inês; Dyack, Brenda; Rolfe, John; Newton, Alice; Borg, Darien; Povilanskas, Ramunas; Brito, Ana C.

Probing the Differential Tissue Distribution and Bioaccumulation Behavior of Per- and Polyfluoroalkyl Substances of Varying Chain-Lengths, Isomeric Structures and Functional Groups in Crucian Carp

Shi, Yali; Vestergren, Robin; Nøst, Therese Haugdahl; Zhou, Zhen; Cai, Yaqi

Understanding the bioaccumulation mechanisms of per- and polyfluoroalkyl substances (PFASs) across different chain-lengths, isomers and functional groups represents a monumental scientific challenge with implications for chemical regulation. Here, we investigate how the differential tissue distribution and bioaccumulation behavior of 25 PFASs in crucian carp from two field sites impacted by point sources can provide information about the processes governing uptake, distribution and elimination of PFASs. Median tissue/blood ratios (TBRs) were consistently <1 for all PFASs and tissues except bile which displayed a distinct distribution pattern and enrichment of several perfluoroalkyl sulfonic acids. Transformation of concentration data into relative body burdens (RBBs) demonstrated that blood, gonads, and muscle together accounted for >90% of the amount of PFASs in the organism. Principal component analyses of TBRs and RBBs showed that the functional group was a relatively more important predictor of internal distribution than chain-length for PFASs. Whole body bioaccumulation factors (BAFs) for short-chain PFASs deviated from the positive relationship with hydrophobicity observed for longer-chain homologues. Overall, our results suggest that TBR, RBB, and BAF patterns were most consistent with protein binding mechanisms although partitioning to phospholipids may contribute to the accumulation of long-chain PFASs in specific tissues.