Found 9849 publications. Showing page 294 of 394:
Prioritizing chemicals and data requirements for exposure and risk assessment. Poster presentation. NILU F
2010
2012
2009
2023
Understanding the bioaccumulation mechanisms of per- and polyfluoroalkyl substances (PFASs) across different chain-lengths, isomers and functional groups represents a monumental scientific challenge with implications for chemical regulation. Here, we investigate how the differential tissue distribution and bioaccumulation behavior of 25 PFASs in crucian carp from two field sites impacted by point sources can provide information about the processes governing uptake, distribution and elimination of PFASs. Median tissue/blood ratios (TBRs) were consistently <1 for all PFASs and tissues except bile which displayed a distinct distribution pattern and enrichment of several perfluoroalkyl sulfonic acids. Transformation of concentration data into relative body burdens (RBBs) demonstrated that blood, gonads, and muscle together accounted for >90% of the amount of PFASs in the organism. Principal component analyses of TBRs and RBBs showed that the functional group was a relatively more important predictor of internal distribution than chain-length for PFASs. Whole body bioaccumulation factors (BAFs) for short-chain PFASs deviated from the positive relationship with hydrophobicity observed for longer-chain homologues. Overall, our results suggest that TBR, RBB, and BAF patterns were most consistent with protein binding mechanisms although partitioning to phospholipids may contribute to the accumulation of long-chain PFASs in specific tissues.
2018
2016
Proceedings of AMAP Workshop on Sources, Emissions and Discharges. Kjeller, 23-24 August 2001. NILU OR
2002
Vinca Institute of Nuclear Sciences
2019
2000
Processes affecting the long-range transport potential of selected brominated flame retardants. NILU PP
2004
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2017
2003
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2006
2011
Progressing to cleaner air: Evaluating non-attainment areas. ETC/ACM Technical Paper, 2012/10
2013