Found 2678 publications. Showing page 55 of 268:
2021
The alkaline comet assay, or single cell gel electrophoresis, is one of the most popular methods for assessing DNA damage in human population. One of the open issues concerning this assay is the identification of those factors that can explain the large inter-individual and inter-laboratory variation. International collaborative initiatives such as the hCOMET project - a COST Action launched in 2016 - represent a valuable tool to meet this challenge. The aims of hCOMET were to establish reference values for the level of DNA damage in humans, to investigate the effect of host factors, lifestyle and exposure to genotoxic agents, and to compare different sources of assay variability. A database of 19,320 subjects was generated, pooling data from 105 studies run by 44 laboratories in 26 countries between 1999 and 2019. A mixed random effect log-linear model, in parallel with a classic meta-analysis, was applied to take into account the extensive heterogeneity of data, due to descriptor, specimen and protocol variability. As a result of this analysis interquartile intervals of DNA strand breaks (which includes alkali-labile sites) were reported for tail intensity, tail length, and tail moment (comet assay descriptors). A small variation by age was reported in some datasets, suggesting higher DNA damage in oldest age-classes, while no effect could be shown for sex or smoking habit, although the lack of data on heavy smokers has still to be considered. Finally, highly significant differences in DNA damage were found for most exposures investigated in specific studies. In conclusion, these data, which confirm that DNA damage measured by the comet assay is an excellent biomarker of exposure in several conditions, may contribute to improving the quality of study design and to the standardization of results of the comet assay in human populations.
2021
Seasonal Variation of Wet Deposition of Black Carbon at Ny-Ålesund, Svalbard
Black carbon (BC) aerosol deposited in and onto Arctic snow increases the snow's absorption of solar radiation and accelerates snowmelt. Concentrations of BC in the Arctic atmosphere and snow are controlled by wet deposition; however, details of this process are poorly understood owing to the scarcity of time-resolved measurements of BC in hydrometeors. We measured mass concentrations of BC in hydrometeors (CMBC) and in air (MBC) with 16% and 15% accuracies, respectively, at Ny-Ålesund, Svalbard during 2012–2019. Median monthly MBC and CMBC values showed similar seasonal variations, being high in winter-spring and low in summer. Median monthly BC wet deposition mass flux (FMBC) was highest in winter and lowest in summer, associated with seasonal patterns of CMBC and precipitation. Seasonally averaged BC size distributions in hydrometeors were similar except for summer. Measurements of MBC and CMBC in spring 2017 showed a size-independent removal efficiency, indicating that BC-containing particles were efficiently activated into cloud droplets. These observations at Ny-Ålesund were compared with observations at Barrow, Alaska, during 2013–2017. The near-surface MBC at Ny-Ålesund and Barrow had similar seasonal patterns; however, the two sites differed in CMBC and FMBC. In summer, CMBC was low at Ny-Ålesund but moderate at Barrow, likely reflecting differences in MBC in the lower troposphere. Seasonally averaged BC size distributions in hydrometeors were similar at both sites, suggesting that average BC size distributions are similar in the Arctic lower troposphere. The efficiency of BC removal tends to be size-independent during transport, leading to the observed similarity.
2021
Eastward-propagating planetary waves prior to the January 2009 sudden stratospheric warming
Eastward-propagating planetary waves (EPWs) were investigated prior to the boreal January 2009 major sudden stratospheric warming (SSW) event simulated by the National Center for Atmospheric Research's Whole Atmosphere Community Climate Model with specified dynamics. About 22 days before SSW onset, a background flow with jet maxima around the upper polar stratosphere and subtropical mesosphere developed due to the net forcing by gravity and planetary waves. The mesospheric wind structure was largely unstable and supported a wave geometry conducive to overreflection. With a zonal phase speed of ∼10 m s−1, EPWs appeared near their turning and critical layers as wavenumber-2 perturbations in the stratosphere and mesosphere. Accompanied by upward EPW activity from the lower stratosphere, EPW growth exhibited characteristics of wave instability and overreflection.
2021
Using the Super Dual Auroral Radar Network observations (clustered around 60°N) and NCAR CESM2.0 extended Whole Atmosphere Community Climate Model nudged with reanalyzes, we examine the climatology of semidiurnal tides in meridional wind associated with the migrating component (SW2) and non‐migrating components of wavenumbers 1 (SW1) and 3 (SW3). We then illustrate their composite response to major sudden stratospheric warmings (SSWs). Peaking in late summer and winter, the climatological SW2 amplitude exceeds SW1 and SW3 except around late Fall and Spring. The winter climatological peak is absent in the model perhaps due to the zonal wind bias at the observed altitudes. The observed SW2 amplitude declines after SSW onset before enhancing ∼10 days later, along with SW1 and SW3. Within the observed region, the simulated SW2 only amplifies after SSW onset, with minimal SW1 and SW3 responses. The model reveals a stronger SW2 response above the observed location, with diminished amplitude before and enhancement after SSW globally. This enhancement appears related to increased equatorial ozone heating and background wind symmetry. The strongest SW1 and SW3 growth occurs in the Southern Hemisphere before SSW. SW2 and quasi‐stationary planetary wave activities are temporally collocated during SSW suggesting that their interactions excite SW1 and SW3. After SSW, the model also reveals (1) semidiurnal‐tide‐like perturbations generated possibly by the interactions between SW2 and westward‐traveling disturbances and (2) the enhancement of migrating semidiurnal lunar tide in the Northern Hemisphere that exceeds non‐migrating tidal and semidiurnal‐tide‐like responses. The simulated eastward‐propagating semidiurnal tides are briefly examined.
2021
Residential wood combustion (RWC) is a major source of air pollutants in the Nordic and many other countries. The emissions of the pollutants have been estimated with inventories on several scopes, e.g. local and national. An important aspect of the inventories is the spatial distribution of the emissions, as it has an effect on health impact assessments. In this study, we present a novel residential wood combustion emission inventory for the Nordic countries based on national inventories and new gridding of the emissions. We compare the emissions of the Nordic inventory, and especially their spatial distribution, to local assessments and European level TNO-newRWC-inventory to assess the spatial proxies used. Common proxies used in the national inventories in the Nordic countries were building data on locations and primary heating methods and questionnaire-based wood use estimates for appliances or primary heating methods. Chimney sweeper register data was identified as good proxy data, but such data may not be available in an applicable format. Comparisons of national inventories to local assessments showed the possibility to achieve similar spatial distributions through nation-wide methods as local ones. However, this won't guarantee that the emissions are similar. Comparison to the TNO-newRWC-inventory revealed the importance of how differences between urban and rural residential wood combustion are handled. The comparison also highlighted the importance of local characteristics of residential wood combustion in the spatial distribution of emissions.
2021
Assessing the impacts of citizen-led policies on emissions, air quality and health
Air pollution is a global challenge, and especially urban areas are particularly affected by acute episodes. Traditional approaches used to mitigate air pollution primarily consider the technical aspects of the problem but not the role of citizen behaviour and day-to-day practices. ClairCity, a Horizon 2020 funded project, created an impact assessment framework considering the role of citizen behaviour to create future scenarios, aiming to improve urban environments and the wellbeing and health of its inhabitants. This framework was applied to six pilot cases: Bristol, Amsterdam, Ljubljana, Sosnowiec, Aveiro Region and Liguria Region, considering three-time horizons: 2025, 2035 and 2050. The scenarios approach includes the Business As Usual (BAU) scenario and a Final Unified Policy Scenarios (FUPS) established by citizens, decision-makers, local planners and stakeholders based on data collected through a citizen and stakeholder co-creation process. Therefore, this paper aims to present the ClairCity outcomes, analysing the quantified impacts of selected measures in terms of emissions, air quality, population exposure, and health. Each case study has established a particular set of measures with different levels of ambition, therefore different levels of success were achieved towards the control and mitigation of their specific air pollution problems. The transport sector was the most addressed by the measures showing substantial improvements for NO2, already with the BAU scenarios, and overall, even better results when applying the citizen-led FUPS scenarios. In some cases, due to a lack of ambition for the residential and commercial sector, the results were not sufficient to fulfil the WHO guidelines. Overall, it was found in all cities that the co-created scenarios would lead to environmental improvements in terms of air quality and citizens’ health compared to the baseline year of 2015. However, in some cases, the health impacts were lower than air quality due to the implementation of the measures not affecting the most densely populated areas. Benefits from the FUPS comparing to the BAU scenario were found to be highest in Amsterdam and Bristol, with further NO2 and PM10 emission reductions around 10%–16% by 2025 and 19%–28% by 2050, compared to BAU.
2021
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2021
Observational studies suggest that part of the North Atlantic Oscillation (NAO) variability may be attributed to the spectral ultra-violet (UV) irradiance variations associated to the 11-year solar cycle. The observed maximum surface pressure response in the North Atlantic occurs 2–4 years after solar maximum, and some model studies have identified that atmosphere–ocean feedbacks explain the multi-year lag. Alternatively, medium-to-high energy electron (MEE) precipitation, which peaks in the declining phase of the solar cycle, has been suggested as a potential cause of this lag. We use a coupled (ocean–atmosphere) climate prediction model and a state-of-the-art MEE forcing to explore the respective roles of irradiance and MEE precipitation on the NAO variability. Three decadal ensemble experiments were conducted over solar cycle 23 in an idealized setting. We found a weak ensemble-mean positive NAO response to the irradiance. The simulated signal-to-noise ratio remained very small, indicating the predominance of internal NAO variability. The lack of multi-annual lag in the NAO response was likely due to lagged solar signals imprinted in temperatures below the oceanic mixed-layer re-emerging equatorward of the oceanic frontal zones, which anchor ocean–atmosphere feedbacks. While there is a clear, yet weak, signature from UV irradiance in the atmosphere and upper ocean over the North Atlantic, enhanced MEE precipitation on the other hand does not lead to any systematic changes in the stratospheric circulation, despite its marked chemical signatures.
2021