Publications

Three-dimensional wind field estimates in complex terrain.

Mocioaca, G.; Sivertsen, B.; Cuculeanu, V.

Thymidine Kinase^+/− Mammalian Cell Mutagenicity Assays for Assessment of Nanomaterials

Chen, Tao; Dusinska, Maria; Elespuru, Rosalie K.

The methods outlined here are part of a series of papers designed specifically for genotoxicity assessment of nanomaterials (NM). Common Considerations such as NM characterization, sample preparation and dose selection, relevant to all genotoxicity assays, are found in an accompanying paper. The present paper describes methods for evaluation of mutagenicity in the mammalian (mouse) thymidine kinase (Tk) gene occurring in L5178Y mouse lymphoma (ML) cells and in the designated TK gene in human lymphoblastoid TK6 cells. Mutations change the functional genotype from TK+/− to TK−/−, detectable as cells surviving on media selective for the lack of thymidine kinase (TK) function. Unlike cells with TK enzyme function, the TK−/− cells are unable to integrate the toxic selection agent, allowing these cells to survive as rare mutant colonies. The ML assay has been shown to detect a broad spectrum of genetic damage, including both small scale (point) mutations and chromosomal alterations. This assay is a widely used mammalian cell gene mutation assay for regulatory purposes and is included in the core battery of genotoxicity tests for regulatory decision-making. The TK6 assay is an assay using a human cell line derived similarly via mutagenic manipulations and optimal selection. Details are provided on the materials required, cell culture methods, selection of test chemical concentrations, cytotoxicity, treatment time, mutation expression, cloning, and data calculation and interpretation. The methods describe the microwell plate version of the assays without metabolic activation.

Frontiers Media S.A.

Thyroid hormone levels of pregnant inuit women and their infants exposed to environmental contaminants.

Dallaire, R.; Muckle, G.; Dewailly, É.; Jacobson, S.W.; Jacobson, J.L.; Sandanger, T.M.; Sandau, C.D.; Ayotte, P.

Tidal Amplification in the Lower Thermosphere during the 2003 October-November Solar Storms

Zhang, Jiarong; Orsolini, Yvan Joseph Georges Emile G.; Limpasuvan, Varavut; Liu, H.; Oberheide, Jens

Tidal Amplification in the Lower Thermosphere during the 2003 October-November Solar Storms

Zhang, Jiarong; Orsolini, Yvan; Limpasuvan, Varavut; Liu, Hanli; Oberheide, Jens

Tidenes miljøgave kommer lille julaften

Berglen, Tore Flatlandsmo; Aspholm, Paul Eric (interview subjects); Andreassen, Erik; Kalinina, Kristina (journalists)

Tilførselsprogrammet 2009. Overvåking av tilførsler og miljøtilstand i Barentshavet og Lofotenområdet. NIVA-rapport, 5980-2010

Green, N.W.; Molvær, J.; Kaste, Ø.; Schrum, C.; Yakushev, E.; Sørensen, K.; Allan, I.; Høgåsen, T.; Christiansen, A.B.; Heldal, H.E.; Klungsøyr, J.; Boitsov, S.; Børsheim, K.Y.; Måge, A.; Julshamn, K.; Aas, W.; Braathen, O.A.; Breivik, K.; Eckhardt, S.; Rudjord, A.L.; Iosjpe, M.; Brungot, A.L.

Tilførselsprogrammet 2010. Passive air and water sampling at Andøya, Bjørnøya and Jan Mayen, 2009-2010. NIVA-rapport, 6188-2011

Allan, I.J.; Aas, W.; Green, N.W.; Bæk, K.; Christiansen, G.; Breivik, K.

Tilførselsprogrammet 2011. Passive air and water sampling at Andøya, Bjørnøya and Jan Mayen, 2010-2011. NIVA-rapport, 6366-2012

Allan, J.; Aas, W.; Langford, K.; Christiansen, G.; Green, N.W.; Breivik, K.; Bæk, K.; Ranneklev, S.

Tilpasninger til klimaendringer i Osloregionen. Rapport til Klimasamarbeidet i Osloregionen. CIENS-rapport 1-2007

Vevatne, J. (red.), Westskog, H. (red.), Engen-Skaugen, T.; Myhre, C.L.; Orderud, G.; Roald, L.A.; Solstad, S.P.; Tryland, I.

Tiltak mot miljøgifter virker.

Nøst, T.H.

Tiltaksutredning for lokal luftkvalitet i Bærum 2025-2030

Weydahl, Torleif; Markelj, Miha; Walker, Sam-Erik

Stiftelsen NILU har, i samarbeid med Transportanalyse AS, utarbeidet trafikk- og luftkvalitetsberegninger for Oslo og Bærum kommuner. Arbeidet omfatter en kartlegging av luftkvaliteten ved trafikkberegninger og utslipps- og spredningsberegninger for relevante forurensningskomponenter (PM10, PM2,5 og NO2) for Dagens situasjon 2022, Referansesituasjonen 2030 og for 2030 med tiltak. Det er beregnet risiko for overskridelse av dagens grenseverdier i forurensningsforskriften og for grenseverdier i revidert EU-direktiv som vil innføres fullt fra 2030.

NILU